Long-term kidney disease (chronic kidney disease or CKD). 2006;5:11. View abstract. View abstract. View abstract. Nagi, M. N. and Almakki, H. A. Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and toxicity. 2019;13(11):420-422. Badary OA, Al-Shabanah OA, Nagi MN, et al. Mouhajir F and et al. Phytomedicine 2005;12(3):194-202. 2010;19(3):206-11. A A Pract. Edris, A. E. Anti-cancer properties of Nigella spp. Surgery: Black seed might slow blood clotting, reduce blood sugar, and increase sleepiness in some people. J Ethnopharmacol 2015;175:147-52. Bamosa, A. O., Ali, B. Nigella sativa improves glycemic control and ameliorates oxidative stress in patients with type 2 diabetes mellitus: placebo controlled participant blinded clinical trial. Yakugaku Zasshi 2006;126(4):301-305. Phytochem.Anal. Sarac G, Kapicioglu Y, Sener S, et al. Effects of Nigella sativa oil and thymoquinone on oxidative stress and neuropathy in streptozotocin-induced diabetic rats. essential oils and their major constituents, thymoquinone and beta-elemene. 2001;110(3-4):239-251. Reindl, W., Yuan, J., Kramer, A., Strebhardt, K., and Berg, T. Inhibition of polo-like kinase 1 by blocking polo-box domain-dependent protein-protein interactions. As a result, it can help preserve the integrity of pancreatic beta cells. Khonche A, Huseini HF, Gholamian M, Mohtashami R, Nabati F, Kianbakht S. Standardized Nigella sativa seed oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease: A randomized, double-blind and placebo-controlled clinical trial. Black seed contains 9 kind of amino acid essential which good for our body need. Saleem R and et al. J Nat.Prod. View abstract. J Ethnopharmacol 1996;52:23-6. Yildiz, F., Coban, S., Terzi, A., Savas, M., Bitiren, M., Celik, H., and Aksoy, N. Protective effects of Nigella sativa against ischemia-reperfusion injury of kidneys. Early research suggests that taking black seed oil by mouth might improve symptoms in people with itchy and inflamed skin. View abstract. Bayrak, O., Bavbek, N., Karatas, O. F., Bayrak, R., Catal, F., Cimentepe, E., Akbas, A., Yildirim, E., Unal, D., and Akcay, A. Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys. 2000;50(9):832-836. Phytother Res 2012;26:1246-8. Beneficial interaction of thymoquinone and sodium valproate in experimental models of epilepsy: Reduction in hepatotoxicity of valproate. Clinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trial. (Praha) 2008;54(1):1-7. J Ethnopharmacol. Taking black seed while being treated for a type of leukemia called acute lymphoblastic leukemia might increase the chances of staying cancer-free once treatment ends. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. A. and Gad el-Rab, M. O. Allergic contact dermatitis: clinical features and profile of sensitizing allergens in Riyadh, Saudi Arabia. J Ethnopharmacol. A., and El Kashef, H. A. Thymoquinone-induced relaxation of guinea-pig isolated trachea. Black seed oil has been used in the treatment of a variety of skin conditions. A., and Memon, R. A. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use black seed. Black seed oil and black seed extract are POSSIBLY SAFE when medical amounts are used short-term. Nephrol.Dial.Transplant. View abstract. Akhtar MS, Riffat S. Field trial of Saussurea lappa roots against nematodes and Nigella sativa seeds against cestodes in children. 5-1-2010;79(9):1251-1260. Current research suggests black … Protective effects of selected medicinal plants against protein degradation, lipid peroxidation and deformability loss of oxidatively stressed human erythrocytes. View abstract. View abstract. Al Jishi, S. A. and Abuo, Hozaifa B. Indian J Physiol Pharmacol 1995;39:59-62. Gali-Muhtasib, H. U., Abou Kheir, W. G., Kheir, L. A., Darwiche, N., and Crooks, P. A. Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes. Diabetes medications are also used to lower blood sugar. Planta Med 2004;70(12):1243-1246. Assayed, M. E. Radioprotective effects of black seed (Nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats. View abstract. Biomed Res Int 2013;2013:953520. View abstract. Akhondian JAV and et al. He T, Xu X. Badary, O. J Enzyme Inhib.Med Chem. Biomed.Sci Instrum. View abstract. J Pak Med Assoc 1991;41:185-7. Nigella sativa L. for prevention of acute radiation dermatitis in breast cancer: A randomized, double-blind, placebo-controlled, clinical trial. View abstract. Mem.Inst.Oswaldo Cruz 2005;100(2):205-211. View abstract. Saudi J Kidney Dis Transpl. essential oils and their major constituents, thymoquinone and beta-elemene. View abstract. Cancer Lett 1992;63:41-6. Stern T and et al. el Dakhakhny, M., Mady, N. I., and Halim, M. A. Nigella sativa L. oil protects against induced hepatotoxicity and improves serum lipid profile in rats. View abstract. Food Chem.Toxicol. Planta Med 2002;68(5):465-466. Epub 2019 Jan 22. View abstract. 2003;85(1):7-14. Oshchepkova, IuI, Veshkurova, O. N., Rogozhin, E. A., Musoliamov, A. K., Smirnov, A. N., Odintsova, T. I., Egorov, TsA, Grishin, E. V., and Salikhov, ShI. Phytomedicine. View abstract. 2005;5(1):195-207. Biochem Mol Biol Int 1999;47:153-9. Neurochem.Res 2008;33(11):2241-2249. The powder delivers soothing benefits and is easily digestible. View abstract. View abstract. 1998;53(2):87-93. Indian J Exp.Biol. Ilhan, A., Gurel, A., Armutcu, F., Kamisli, S., and Iraz, M. Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice. View abstract. Eur.J Pharmacol. View abstract. Al-Jenoobi FI, Al-Suwayeh SA, Muzaffar I, et al. Sethi, G., Ahn, K. S., and Aggarwal, B. Abdel-Wahhab, M. A. and Aly, S. E. Antioxidant property of Nigella sativa (black cumin) and Syzygium aromaticum (clove) in rats during aflatoxicosis. eMedicineHealth does not provide medical advice, diagnosis or treatment. Muneera KE, Majeed A, Naveed AK. Rooney, S. and Ryan, M. F. Effects of alpha-hederin and thymoquinone, constituents of Nigella sativa, on human cancer cell lines. Mansour, M. A., Nagi, M. N., El Khatib, A. S., and Al Bekairi, A. M. Effects of thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT-diaphorase in different tissues of mice: a possible mechanism of action. Effects of thymoquinone, the major constituent of Nigella sativa seeds, on the contractile responses of rat vas deferens. Black seed, considered to be a magical seed, is truly one of the most powerful seeds. 2003;41:616-621. Isik, A. F., Kati, I., Bayram, I., and Ozbek, H. A new agent for treatment of acute respiratory distress syndrome: thymoquinone. Biomed.Sci Instrum. 8-15-2007;67(16):7782-7788. Shawki M, El Wakeel L, Shatla R, et al. BMC Complement Altern Med 2016;16:471. View abstract. View abstract. View abstract. Saudi Med J 2009;30(3):443-445. View abstract. Acta Diabetol. View abstract. 2. 2003;85(1):7-14. Dahri, A. H., Chandiol, A. M., Rahoo, A. Phytother.Res 2003;17(8):942-946. Neurochem.Res 2008;33(3):579-588. Shoieb, A. M., Elgayyar, M., Dudrick, P. S., Bell, J. L., and Tithof, P. K. In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone. View abstract. A., Jyothy, A., and Lei, D. K. Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa. Carbohydr.Res 1-5-2009;344(1):149-151. View abstract. American Journal of Applied Sciences. When taking medication – Always consult a doctor before using black seed oil. J Ethnopharmacol. View abstract. Landa, P., Kokoska, L., Pribylova, M., Vanek, T., and Marsik, P. In vitro anti-inflammatory activity of carvacrol: Inhibitory effect on COX-2 catalyzed prostaglandin E(2) biosynthesis. 1965;15(10):1227-1229. Asthma. A., Randhawa, M. A., and Shaikh, N. A. But taking black seed oil does not seem to work. View abstract. Mutat.Res 4-26-2002;516(1-2):11-17. Phytother.Res 2007;21(9):898-899. 10-30-2009;2(4-5):163-172. Phytomedicine 2005;12(3):194-202. View abstract. World J Gastroenterol. The effect of thymol and its derivatives on reactions generating reactive oxygen species. Post-coital contraceptive efficacy of the seeds of Black seed in rats. In foods, black seed is used as a flavoring or spice. 2009;7(1):9. View abstract. A., El Masry, M. H., and Bogdady, H. H. Plant crude extracts could be the solution: extracts showing in vivo antitumorigenic activity. The effect of thymoquinone on blood lipids in rats. 2009;45:274-279. Kocyigit, Y., Atamer, Y., Uysal, E., and Baran, M. S. Effect of nigella (Nigella sativa L.) seeds on hematological parameters in rats. Pagola, S., Benavente, A., Raschi, A., Romano, E., Molina, M. A., and Stephens, P. W. Crystal structure determination of thymoquinone by high-resolution X-ray powder diffraction. View abstract. C R.Biol. Bleeding disorders: Black seed might slow blood clotting and increase the risk of bleeding. View abstract. J Ethnopharmacol. El Hissy, F. T., Abdel-Hafez, S. I., and Abdel-Kader, M. I. Rhizosphere fungi of five plants in Egypt. View abstract. Nagi MN, Alam K, Badary OA, et al. View abstract. Effect of Nigella sativa oil versus metformin on glycemic control and biochemical parameters of newly diagnosed type 2 diabetes mellitus patients. View abstract. Evaluation of safety and efficacy profile of Nigella sativa oil as an add-on therapy, in addition to alpha-keto analogue of essential amino acids in patients with chronic kidney disease. Ann Allergy 1993;70:237-42. 1979;17(11):1264-1265. 2008;28(1):11-14. View abstract. View abstract. 2008;28(1):11-14. View abstract. A., El Sayed, R., Mashhour, A., Billedo, G., El Doush, I., and Al Saleh, I. Med Sci Monit. Boskabady, M. H., Keyhanmanesh, R., and Saadatloo, M. A. Relaxant effects of different fractions from Nigella sativa L. on guinea pig tracheal chains and its possible mechanism(s). Int J Clin Pharmacol.Ther 2008;46(6):295-306. Early research shows that applying black seed oil to the knee for 3-4 weeks can help relieve knee pain caused by osteoarthritis. View abstract. 11-14-2005;11(42):6662-6666. View abstract. Herba Polonica (Poland) 2007;53:279-285. 2006;44(9):745-748. View abstract. Steinmann, A., Schatzle, M., Agathos, M., and Breit, R. Allergic contact dermatitis from black cumin (Nigella sativa) oil after topical use. View abstract. View abstract. Amelioration of aluminum toxicity with black seed supplement on rats. J Ethnopharmacol. Islam, S. K., Ahsan, M., Hassan, C. M., and Malek, M. A. Antifungal activities of the oils of Nigella sativa seeds. Phytother Res. Biochem.Pharmacol. Nikakhlagh S, Rahim F, Aryani FH, Syahpoush A, Brougerdnya MG, Saki N. Herbal treatment of allergic rhinitis: the use of nigella sativa. 2003;17(10):1209-1214. el Tahir, K. E., Ashour, M. M., and al Harbi, M. M. The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea-pigs: elucidation of the mechanism(s) of action. Int J Biochem Cell Biol. The fiber in flaxseed is found primarily in the seed coat. Khalife, K. H. and Lupidi, G. Reduction of hypervalent states of myoglobin and hemoglobin to their ferrous forms by thymoquinone: the role of GSH, NADH and NADPH. 2004;93(1):19-23. View abstract. View abstract. Obtained from US Patent and Trademark Ofc on April 12, 2000. www.uspto.gov/patft/index.htm. 12-21-2005;11(47):7499-7507. Nigella sativa L. seeds modulate mood, anxiety and cognition in healthy adolescent males. Plant Foods Hum.Nutr. Boskabady MH and et al. Toxicity caused by the drug methotrexate. Antimotility and antidiarrheal effects of Nigella sativa Linn. View abstract. Hosseinzadeh, H., Parvardeh, S., Nassiri-Asl, M., and Mansouri, M. T. Intracerebroventricular administration of thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats. Biol.Trace Elem.Res 2007;115(2):157-167. View abstract. Enomoto, S., Asano, R., Iwahori, Y., Narui, T., Okada, Y., Singab, A. N., and Okuyama, T. Hematological studies on black cumin oil from the seeds of Nigella sativa L. Biol.Pharm.Bull 2001;24(3):307-310. Ann Saudi Med 2017;37:64-71. El Abhar, H. S., Abdallah, D. M., and Saleh, S. Gastroprotective activity of Nigella sativa oil and its constituent, thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats. Al Naggar, T. B., Gomez-Serranillos, M. P., Carretero, M. E., and Villar, A. M. Neuropharmacological activity of Nigella sativa L. extracts. 2007;21(5):559-566. International Journal of Pharmacognosy (Netherlands). View abstract. View abstract. View abstract. Life Sci. Stay on the safe side and avoid use. View abstract. Asgari S and et al. View abstract. Antitumour principles from Black seed seeds. It's unclear if this improvement is due to black seed or other ingredients. Jpn.J Vet.Res 2008;56(3):119-128. 2005;42(1):23-30. El Gouhary, I., Mohamed, A., Suleiman, S., and Benghuzzi, H. Comparison of the amelioration effects of two enzyme inducers on the inflammatory process of experimental allergic encephalitis (EAE) using immunohistochemical technique. Zaoui, A., Cherrah, Y., Alaoui, K., Mahassine, N., Amarouch, H., and Hassar, M. Effects of Nigella sativa fixed oil on blood homeostasis in rat. Cornea 2007;26(6):715-719. Effect of Nigella sativa supplementation on oxidative stress and antioxidant parameters: A meta-analysis of randomized controlled trials. Chehl, N., Chipitsyna, G., Gong, Q., Yeo, C. J., and Arafat, H. A. Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells. 2010;25(2-3):307-314. View abstract. View abstract. View abstract. 1997;5:110-113. Salem, M. L. and Hossain, M. S. Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. The effect of essential oil extracted from Nigella sativa (L.) seeds on human neutrophil functions. 2005;25(3B):2199-2204. Effect of Nigella sativa seed administration on prevention of febrile neutropenia during chemotherapy among children with brain tumors. A., Abd-Ellah, M. F., El Mahdy, M. A., Salama, S. A., and Hamada, F. M. Anticlastogenic activity of thymoquinone against benzo(a)pyrene in mice. Oberg, F., Haseeb, A., Ahnfelt, M., Ponten, F., Westermark, B., and El Obeid, A. Herbal melanin activates TLR4/NF-kappaB signaling pathway. Tardy, F., Benghuzzi, H., and Tucci, M. The role of thymoquinone and epigallocatechin-3-gallate on the viability of mrc-5 fibroblasts in culture - biomed 2009. J Med Food 2005;8(4):488-493. cyclosporine pharmacokinetics. View abstract. 2009;1(1):17. Ozbek, H. Determination of lethal doses of volatile and fixed oils of several plants. View abstract. Effectiveness, safety, and tolerability of powdered Nigella sativa (kalonji) seed in capsules on serum lipid levels, blood sugar, blood pressure, and body weight in adults: results of a randomized, double-blind controlled trial. 2003;17(4):299-305. Therefore, you may wonder whether eating black sesame seeds is also good for hair and skin health. J Physiol Pharmacol. Eur.J Pharmacol. View abstract. J Altern.Complement Med 2009;15(6):639-644. In ancient texts and historical documents black cumin seed is noted for its therapeutic attributes and ability to support the body in its own natural healing processes. Chin Med 2009;4:19. View abstract. Chakravarty N. Inhibition of histamine release from mast cells by nigellone. Keshri G, Singh MM, Lakshmi V, Kamboj VP. Norwood, A. Hepatitis C. Early research shows that taking black seed oil daily for 3 months reduces viral load in people with hepatitis C. It also seems to reduce lower limb swelling. Kamal EH and et al. Historically, black seed has been used for headache, toothache, nasal congestion, and intestinal worms. Khan, N. and Sultana, S. Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliferative response by Nigella sativa. Koshak A, Wei L, Koshak E, et al. Khan MT and et al. Nat.Prod.Res 2009;23(2):138-148. Iranian Journal of Diabetes & Lipid Disorders (IRANIAN J DIABETES LIPID DISORD) 2007;6(3):E29. El Mahmoudy, A., Shimizu, Y., Shiina, T., Matsuyama, H., Nikami, H., and Takewaki, T. Macrophage-derived cytokine and nitric oxide profiles in type I and type II diabetes mellitus: effect of thymoquinone. View abstract. Biol.Trace Elem.Res 2003;96(1-3):263-270. Cancer of the white blood cells (leukemia). el Dakhakhny, M., Mady, N., Lembert, N., and Ammon, H. P. The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions. Kanter, M. Effects of Nigella sativa seed extract on ameliorating lung tissue damage in rats after experimental pulmonary aspirations. Ajenuz, Aranuel, Baraka, Black Caraway, Black Cumin, Black Cumin Seed Oil, Charnuska, Cheveux de VÃ©nus, Cominho Negro, Comino Negro, Cumin Noir, Cyah Dane, Fennel Flower, Fitch, Graine de Nigelle, Graine Noire, Habatul Sauda, Habbatul Baraka, Kalajaji, Kalajira, Kalonji, Ketsah, La Grainer Noire, Love in a Mist, Mugrela, Nielle, Nigella sativa, Nigelle de CrÃªte, Nigelle CultivÃ©e, Nutmeg Flower, Poivrette, Roman-Coriander, Schwarzkummel, Seed of Blessing, Siyah Dane, Shoniz, Small Fennel, Toute Ãpice, Upakuncika. 2004;18(5):395-398. View abstract. Research shows that applying a gel containing black seed oil to the breasts during the menstrual cycle reduces pain in women with breast pain. Morsi, N. M. Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria. 2009;47:77-80. Diabetes: Black seed might lower blood sugar levels in some people. 2013;27(12):1849-53. Amizadeh S, Rashtchizadeh N, Khabbazi A, et al. 1997;75(12):1356-1361. Azza, M. M. Nadia M. M. Sohair S. Sativa seeds against. View abstract. Zaoui, A., Cherrah, Y., Lacaille-Dubois, M. A., Settaf, A., Amarouch, H., and Hassar, M. [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]. 2001;76(1):45-48. Kalus, U., Pruss, A., Bystron, J., Jurecka, M., Smekalova, A., Lichius, J. J., and Kiesewetter, H. Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases. Ren Fail. View abstract. Cancer Biol.Ther 2007;6(2):160-169. Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, et al. The effects of Nigella sativa on atherosclerosis and its new risk factors in hypercholesterolemic rabbits. View abstract. Planta Med 2008;74(2):105-108. View abstract. Antimicrobial thymohydroquinones of Moroccan Nigella sativa seeds detected by electron spin resonance. Effectiveness of topical Nigella sativa for vitiligo treatment. 2008;20(2):118-124. View abstract. We currently have no information for BLACK SEED Interactions.
Unhealthy Lifestyle Effects, Chocolate Coconut Balls With Condensed Milk, White Lily Self-rising Flour, Taylormade M6 Irons For Sale Uk, Torta Al Testo Perugia Dove Mangiarla, Beyerdynamic T1 2nd Gen Vs Dt 1990, Panasonic Hc-x1 Specs,